April 27, 2020
Title: Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients
Hospitalized With COVID-19 in the New York City Area
Publisher: JAMA Network
Publication: April 22, 2020
12.2% received invasive mechanical ventilation, 3.2% needed renal replacement therapy, and 21% died.
April 20, 2020
Title: COVID-19 Clinical Guidance Repository, Assoc. American Medical Colleges (AAMC)
Key Takeaway: Summary of up-to-date management guidelines from leading academic centers.
Title: Absence of 2019 Novel Coronavirus in Semen and Testes of COVID-19 Patients
Publication: Biology of Reproduction, April 16, 2020
Key Takeaway: This small case series demonstrates that the Covid-19 virus is absent from the semen and testes in men infected by COVID-19 at both acute and recovery phases making it highly unlikely that the 2019-nCov can be sexually transmitted by men. However other adjacent activities (e.g. kissing and close contact) can still result in transmission.
Title: Nature Article - Temporal dynamics in viral shedding and transmissibility of COVID-19
Publication: Nature, April 15, 2020
Key Takeaway: In 94 COVID-19 positive patients, the authors observed the highest viral load in throat swabs at the time of symptom onset, and inferred that infectiousness peaked on or before symptom onset. They estimated that 44% (95% confidence interval, 25–69%) of secondary cases were infected during the index cases’ presymptomatic stage. The highest risk was in clustered household settings, and non-compliance with quarantine.
Title: How does Coronavirus Kill? Clinicians trace a ferocious rampage through the body from brain to toes
Publication: Science Magazine, April 17, 2009
Key Takeaway: This non-technical, “big picture” piece highlights the multi-system implications of clinical disease with novel coronavirus. COVID pathology is not limited to the lungs. While the pulmonary system is certainly ground zero, its reach can extend to many organs including the heart and blood vessels, kidneys, gut, and brain.
March 31, 2013
Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province
Care Recommendations for Home-Based Ventilation Patient
GW COVID-19 Inpatient Care Algorithm
Cardiology and Covid-19
Title: Covid 19 Primer: Virtual Patient Simulation
Publisher: New England Journal of Medicine
Publication Date: April 2020
Key Takeaway: Resource for Internal Medicine interns – COVID patient simulator.