Skip to main content
It looks like you're using Internet Explorer 11 or older. This website works best with modern browsers such as the latest versions of Chrome, Firefox, Safari, and Edge. If you continue with this browser, you may see unexpected results.

COVID-19 Intelligence Report: Gastroenterology

May 18, 2020

Title: Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis

Publisher: The Lancet Gastroenterology and Hepatology

Publication Date: May 12, 2020

URL: https://www.thelancet.com/pdfs/journals/langas/PIIS2468-1253(20)30126-6.pdf

Key Takeaway:  Meta-analysis of 35 studies (6686 patients) revealed pooled prevalence of digestive symptoms (often nausea/vomiting, diarrhea, or loss of appetite) was 15%, abnormal liver function was 19%. Subgroup analysis showed patients with severe COVID-19 had significantly higher rates of gastrointestinal symptoms and liver injury compared with those with non-severe disease (odds ratio [OR] 1.60 [95% CI 1.09–2.36]; p=0.0020; I²=44%), OR (2.20 [1.60–3.02]; p<0.00001; I²=36% respectively). Pediatric COVID patients had a similar prevalence of GI symptoms to those of adults.

May 11, 2020

Title: New COVID-19 guidance for gastroenterologists

Publisher: American Gastroenterological Association

Publication Date: 04 May 2020

URL: https://www.gastro.org/news/new-covid-19-guidance-for-gastroenterologists

Key Takeaway: GI symptoms might not be as common as originally thought in COVID.  Abnormalities in liver function tests, however, should prompt thorough evaluation.

The Himmelfarb Health Sciences Library
Questions? Ask us.
Creative Commons License
All LibGuides by Himmelfarb Health Sciences Library are licensed under a
Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.

The George Washington University