Jan - June 2020 - Internal Medicine Residency Readings - Research Guides at George Washington University

Critical Care Primer

Critical Care Primer: Educational Resources for Non-ICU Clinicians
Link to free online training by the Society of Critical Care Medicine as well as additional information resources including: video tutorials, handbooks, and key review articles plus weekly clinical updates from the GW Division of Infectious Diseases.

Education

Instructions:

Access NEJM Resident 360 via Himmelfarb Library to create a free personal account using your @gwu.edu email address.
After creating your account, you may access via the library or by direct access to NEJM Resident 360.

Access: NEJM Interactive Cases

Access: NEJM Videos in Clinical Medicine

June 2, 2020

Invasive Candidiasis (NEJM review)
Kullberg BJ, Arendrup MC. Invasive Candidiasis. N Engl J Med. 2015;373(15):1445‐1456. doi:10.1056/NEJMra1315399
Invasive candidiasis
Pappas PG, Lionakis MS, Arendrup MC, Ostrosky-Zeichner L, Kullberg BJ. Invasive candidiasis. Nat Rev Dis Primers. 2018;4:18026. Published 2018 May 11. doi:10.1038/nrdp.2018.26

May 28, 2020

Hypertensive Disorders of Pregnancy
Leeman L, Dresang LT, Fontaine P. Hypertensive Disorders of Pregnancy. Am Fam Physician. 2016;93(2):121‐127.
Gestational Hypertension and Preeclampsia
Croke L. Gestational Hypertension and Preeclampsia: A Practice Bulletin from ACOG. Am Fam Physician. 2019;100(10):649‐650.
HELLP syndrome
Dusse LM, Alpoim PN, Silva JT, Rios DR, Brandão AH, Cabral AC. Revisiting HELLP syndrome. Clin Chim Acta. 2015;451(Pt B):117‐120. doi:10.1016/j.cca.2015.10.024
Hypothyroidism in Pregnancy
Taylor PN, Lazarus JH. Hypothyroidism in Pregnancy. Endocrinol Metab Clin North Am. 2019;48(3):547‐556. doi:10.1016/j.ecl.2019.05.010

May 21, 2020

Approach to Patients with Eosinophilia
Kuang FL. Approach to Patients with Eosinophilia. Med Clin North Am. 2020;104(1):1‐14. doi:10.1016/j.mcna.2019.08.005
Smudge cells
From Non-Neoplastic Morphologic Abnormalities of White Blood Cells and Macrophages in Hematopathology (3rd ed.)
Angioimmunoblastic T-cell lymphoma: the many-faced lymphoma
Lunning MA, Vose JM. Angioimmunoblastic T-cell lymphoma: the many-faced lymphoma. Blood. 2017;129(9):1095‐1102. doi:10.1182/blood-2016-09-692541
Angioimmunoblastic T-Cell Lymphoma
Broccoli A, Zinzani PL. Angioimmunoblastic T-Cell Lymphoma. Hematol Oncol Clin North Am. 2017;31(2):223‐238. doi:10.1016/j.hoc.2016.12.001

May 19, 2020

A Shocking Turn of Events
DeFilippis EM, Vaidya A, Braun D, Lakdawala N, Sobieszczyk P. A Shocking Turn of Events. N Engl J Med. 2018;378(21):e29. doi:10.1056/NEJMimc1710576
Brugada syndrome
Brugada J, Campuzano O, Arbelo E, Sarquella-Brugada G, Brugada R. Present Status of Brugada Syndrome: JACC State-of-the-Art Review. J Am Coll Cardiol. 2018;72(9):1046‐1059. doi:10.1016/j.jacc.2018.06.037
Superior Vena Cava Syndrome
Zimmerman S, Davis M. Rapid Fire: Superior Vena Cava Syndrome. Emerg Med Clin North Am. 2018;36(3):577‐584. doi:10.1016/j.emc.2018.04.011

May 14, 2020

Fatigue
Rosenthal TC, Majeroni BA, Pretorius R, Malik K. Fatigue: an overview. Am Fam Physician. 2008;78(10):1173‐1179.
Voluntary and involuntary movements
Ugawa Y. Voluntary and involuntary movements: A proposal from a clinician [published online ahead of print, 2019 Oct 18]. Neurosci Res. 2019;S0168-0102(19)30434-1. doi:10.1016/j.neures.2019.10.001
Hyponatremia
Henry DA. In The Clinic: Hyponatremia. Ann Intern Med. 2015;163(3):ITC1‐ITC19. doi:10.7326/AITC201508040
Management of hyponatremia: causes, clinical aspects, differential diagnosis and treatment
Peri A. Management of hyponatremia: causes, clinical aspects, differential diagnosis and treatment. Expert Rev Endocrinol Metab. 2019;14(1):13‐21. doi:10.1080/17446651.2019.1556095
Antibody-LGI1 limbic encephalitis
Bing-Lei W, Jia-Hua Z, Yan L, et al. Three cases of antibody-LGI1 limbic encephalitis and review of literature. Int J Neurosci. 2019;129(7):642‐648. doi:10.1080/00207454.2018.1512985

May 12, 2020

Hypernatremia
Liamis G, Filippatos TD, Elisaf MS. Evaluation and treatment of hypernatremia: a practical guide for physicians. Postgrad Med. 2016;128(3):299‐306. doi:10.1080/00325481.2016.1147322
Diabetes insipidus
Christ-Crain M, Bichet DG, Fenske WK, et al. Diabetes insipidus. Nat Rev Dis Primers. 2019;5(1):54. Published 2019 Aug 8. doi:10.1038/s41572-019-0103-2

May 7, 2020

Syncope: Evaluation and Differential Diagnosis
Runser LA, Gauer RL, Houser A. Syncope: Evaluation and Differential Diagnosis. Am Fam Physician. 2017;95(5):303‐312.
Approach to pancytopenia: Diagnostic algorithm for clinical hematologists
Gnanaraj J, Parnes A, Francis CW, Go RS, Takemoto CM, Hashmi SK. Approach to pancytopenia: Diagnostic algorithm for clinical hematologists. Blood Rev. 2018;32(5):361‐367. doi:10.1016/j.blre.2018.03.001
Novel Developments in Leukopenia and Pancytopenia
Onuoha C, Arshad J, Astle J, Xu M, Halene S. Novel Developments in Leukopenia and Pancytopenia. Prim Care. 2016;43(4):559‐573. doi:10.1016/j.pop.2016.07.005

May 5, 2020

Cutaneous Adverse Drug Reactions: How to Identify the Trigger
Zambernardi A, Label M. Cutaneous Adverse Drug Reactions: How to Identify the Trigger. Reacciones cutáneas adversas a medicamentos: cómo identificar el desencadenante. Actas Dermosifiliogr. 2018;109(8):699‐707. doi:10.1016/j.ad.2018.02.017
Acute generalized exanthematous pustulosis
Szatkowski J, Schwartz RA. Acute generalized exanthematous pustulosis (AGEP): A review and update. J Am Acad Dermatol. 2015;73(5):843‐848. doi:10.1016/j.jaad.2015.07.017
Severe cutaneous adverse reactions to drugs
Duong TA, Valeyrie-Allanore L, Wolkenstein P, Chosidow O. Severe cutaneous adverse reactions to drugs [published correction appears in Lancet. 2017 Oct 28;390(10106):1948]. Lancet. 2017;390(10106):1996‐2011. doi:10.1016/S0140-6736(16)30378-6
Severe Cutaneous Adverse Drug Reactions: Presentation, Risk Factors, and Management
Mustafa SS, Ostrov D, Yerly D. Severe Cutaneous Adverse Drug Reactions: Presentation, Risk Factors, and Management. Curr Allergy Asthma Rep. 2018;18(4):26. Published 2018 Mar 24. doi:10.1007/s11882-018-0778-6
Classification of the cutaneous manifestations of COVID-19
Galván Casas C, Català A, Carretero Hernández G, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases [published online ahead of print, 2020 Apr 29]. Br J Dermatol. 2020;10.1111/bjd.19163. doi:10.1111/bjd.19163
Skin damage among health care workers managing coronavirus disease-2019
Lan J, Song Z, Miao X, et al. Skin damage among health care workers managing coronavirus disease-2019. J Am Acad Dermatol. 2020;82(5):1215‐1216. doi:10.1016/j.jaad.2020.03.014

April 30, 2020

The Current State of Critical Limb Ischemia: A Systematic Review
Farber A, Eberhardt RT. The Current State of Critical Limb Ischemia: A Systematic Review. JAMA Surg. 2016;151(11):1070‐1077. doi:10.1001/jamasurg.2016.2018
Diagnosis and Management of Acute Ischemic Stroke
Hasan TF, Rabinstein AA, Middlebrooks EH, et al. Diagnosis and Management of Acute Ischemic Stroke. Mayo Clin Proc. 2018;93(4):523‐538. doi:10.1016/j.mayocp.2018.02.013
Marantic endocarditis: Nonbacterial Thrombotic Endocarditis: Pathogenesis, Diagnosis, and Management.
Liu J, Frishman WH. Nonbacterial Thrombotic Endocarditis: Pathogenesis, Diagnosis, and Management. Cardiol Rev. 2016;24(5):244‐247. doi:10.1097/CRD.0000000000000106

April 28, 2020

Porphyria
Bissell DM, Anderson KE, Bonkovsky HL. Porphyria. N Engl J Med. 2017;377(9):862–872. doi:10.1056/NEJMra1608634

April 23, 2020

Melatonin as a potential adjuvant treatment
Zhang R, Wang X, Ni L, et al. COVID-19: Melatonin as a potential adjuvant treatment. Life Sci. 2020;250:117583. doi:10.1016/j.lfs.2020.117583
Melatonin reduces the need for sedation in ICU patients: a randomized controlled trial.
Mistraletti G, Umbrello M, Sabbatini G, et al. Melatonin reduces the need for sedation in ICU patients: a randomized controlled trial. Minerva Anestesiol. 2015;81(12):1298–1310.
Milk-alkali syndrome
Medarov BI. Milk-alkali syndrome. Mayo Clin Proc. 2009;84(3):261–267. doi:10.1016/S0025-6196(11)61144-0
Clinical Problem Solvers
Recommended by Dr. Michael Simon

April 22, 2020

High-flow nasal cannula oxygen in adults: an evidence-based assessment
Drake, M. G. (2018). High-flow nasal cannula oxygen in adults: an evidence-based assessment. Annals of the American Thoracic Society, 15(2), 145-155.

April 16, 2020

Pharyngitis: Approach to diagnosis and treatment
Sykes EA, Wu V, Beyea MM, Simpson MTW, Beyea JA. Pharyngitis: Approach to diagnosis and treatment. Can Fam Physician. 2020;66(4):251–257.

The Modern Epidemic of Syphilis
Ghanem KG, Ram S, Rice PA. The Modern Epidemic of Syphilis. N Engl J Med. 2020;382(9):845–854. doi:10.1056/NEJMra1901593

April 14, 2020

Otitis Media with Effusion
Atkinson H, Wallis S, Coatesworth AP. Otitis media with effusion. Postgrad Med. 2015;127(4):381–385. doi:10.1080/00325481.2015.1028317

Evaluation and treatment of shoulder pain
Greenberg DL. Evaluation and treatment of shoulder pain. Med Clin North Am. 2014;98(3):487–504. doi:10.1016/j.mcna.2014.01.016

Lyme Disease
Hu LT. Lyme Disease. Ann Intern Med. 2016;164(9):ITC65–ITC80. doi:10.7326/AITC201605030

Clinical manifestations of granulomatosis with polyangiitis: key considerations and major features
Grygiel-Górniak B, Limphaibool N, Perkowska K, Puszczewicz M. Clinical manifestations of granulomatosis with polyangiitis: key considerations and major features. Postgrad Med. 2018;130(7):581–596. doi:10.1080/00325481.2018.1503920

Dr. Friedrich Wegener and the ACCP
Rosen MJ. Dr. Friedrich Wegener, the ACCP, and History. Chest. 2007;132(3):739–741. doi:10.1378/chest.07-0769

April 9, 2020

Clinical Problem Solving: A Rapid Change in Pressure (Interactive module)
D'Silva K, Cockrill B, Anderson WJ, Miller AL, Loscalzo J. A Rapid Change in Pressure. N Engl J Med. 2020;382(6):563–570. doi:10.1056/NEJMcps1814993

Clinical Problem Solving: A Rapid Change in Pressure (PDF)
D'Silva K, Cockrill B, Anderson WJ, Miller AL, Loscalzo J. A Rapid Change in Pressure. N Engl J Med. 2020;382(6):563–570. doi:10.1056/NEJMcps1814993

Determinants of plasma acid-base balance
Kellum JA. Determinants of plasma acid-base balance. Crit Care Clin. 2005;21(2):329–346. doi:10.1016/j.ccc.2005.01.010

Pulmonary Hypertension
Kim D, George MP. Pulmonary Hypertension. Med Clin North Am. 2019;103(3):413–423. doi:10.1016/j.mcna.2018.12.002

Right Heart Catheterizaation
Callan P, Clark AL. Right heart catheterisation: indications and interpretation. Heart. 2016;102(2):147–157. doi:10.1136/heartjnl-2015-307786

April 7, 2020

Gastric adenocarcinoma
Ajani JA, Lee J, Sano T, Janjigian YY, Fan D, Song S. Gastric adenocarcinoma. Nat Rev Dis Primers. 2017;3:17036. Published 2017 Jun 1. doi:10.1038/nrdp.2017.36

Trends in management of phlegmasia cerulea dolens
Chinsakchai K, Ten Duis K, Moll FL, de Borst GJ. Trends in management of phlegmasia cerulea dolens. Vasc Endovascular Surg. 2011;45(1):5–14. doi:10.1177/1538574410388309

April 2, 2020

Current Status of Inotropes in Heart Failure
Ginwalla M, Tofovic DS. Current Status of Inotropes in Heart Failure. Heart Fail Clin. 2018;14(4):601–616. doi:10.1016/j.hfc.2018.06.010

Current Status of Left Ventricular Assist Device Therapy
Sajgalik P, Grupper A, Edwards BS, et al. Current Status of Left Ventricular Assist Device Therapy. Mayo Clin Proc. 2016;91(7):927–940. doi:10.1016/j.mayocp.2016.05.002

Novel Insights and Treatment Strategies for Right Heart Failure
Lin W, Poh AL, Tang WHW. Novel Insights and Treatment Strategies for Right Heart Failure. Curr Heart Fail Rep. 2018;15(3):141–155. doi:10.1007/s11897-018-0389-5

Aortic insufficiency & LVAD
Noly PE, Pagani FD, Noiseux N, et al. Continuous-Flow Left Ventricular Assist Devices and Valvular Heart Disease: A Comprehensive Review. Can J Cardiol. 2020;36(2):244–260. doi:10.1016/j.cjca.2019.11.022

Heart transplant: indications & contraindications
Guglin M, Zucker MJ, Borlaug BA, et al. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. J Am Coll Cardiol. 2020;75(12):1471–1487. doi:10.1016/j.jacc.2020.01.034

Diagnosis and management of maturity onset diabetes of the young (MODY)
Thanabalasingham G, Owen KR. Diagnosis and management of maturity onset diabetes of the young (MODY). BMJ. 2011;343:d6044. Published 2011 Oct 19. doi:10.1136/bmj.d6044

Euglycemic diabetic ketoacidosis
Barski L, Eshkoli T, Brandstaetter E, Jotkowitz A. Euglycemic diabetic ketoacidosis. Eur J Intern Med. 2019;63:9–14. doi:10.1016/j.ejim.2019.03.014

Median arcuate ligament syndrome
Goodall R, Langridge B, Onida S, Ellis M, Lane T, Davies AH. Median arcuate ligament syndrome [published online ahead of print, 2019 Dec 24]. J Vasc Surg. 2019;S0741-5214(19)32642-4. doi:10.1016/j.jvs.2019.11.012

Central Hypothyroidism
Beck-Peccoz P, Rodari G, Giavoli C, Lania A. Central hypothyroidism - a neglected thyroid disorder. Nat Rev Endocrinol. 2017;13(10):588–598. doi:10.1038/nrendo.2017.47

Hypopituitarism
Higham CE, Johannsson G, Shalet SM. Hypopituitarism. Lancet. 2016;388(10058):2403–2415. doi:10.1016/S0140-6736(16)30053-8

Subclinical Hyperthyroidism
Biondi B, Cooper DS. Subclinical Hyperthyroidism. N Engl J Med. 2018;378(25):2411–2419. doi:10.1056/NEJMcp1709318

March 31, 2020

Acute diarrhea
Barr W, Smith A. Acute diarrhea. Am Fam Physician. 2014;89(3):180–189.

Secretory diarrhoea: mechanisms and emerging therapies
Thiagarajah JR, Donowitz M, Verkman AS. Secretory diarrhoea: mechanisms and emerging therapies. Nat Rev Gastroenterol Hepatol. 2015;12(8):446–457. doi:10.1038/nrgastro.2015.111

Hyperthyroidism
De Leo S, Lee SY, Braverman LE. Hyperthyroidism. Lancet. 2016;388(10047):906–918. doi:10.1016/S0140-6736(16)00278-6

Hyperthyroidism: Diagnosis and Treatment
Kravets I. Hyperthyroidism: Diagnosis and Treatment. Am Fam Physician. 2016;93(5):363–370.

March 26, 2020

Rapid Interpretation of EKG's by Dale Dubin
ISBN: 0912912065
Publication Date: 2000

Diagnosis and clinical management of long-QT syndrome
Steinberg C. Diagnosis and clinical management of long-QT syndrome. Curr Opin Cardiol. 2018;33(1):31–41. doi:10.1097/HCO.0000000000000465

Electrocardiographic manifestations of severe hyperkalemia
Littmann L, Gibbs MA. Electrocardiographic manifestations of severe hyperkalemia. J Electrocardiol. 2018;51(5):814–817. doi:10.1016/j.jelectrocard.2018.06.018

Rapid Fire: Hypercalcemia
Carrick AI, Costner HB. Rapid Fire: Hypercalcemia. Emerg Med Clin North Am. 2018;36(3):549–555. doi:10.1016/j.emc.2018.04.008

Multifocal Atrial Tachycardia (MAT)
Custer AM, Yelamanchili VS, Lappin SL. Multifocal Atrial Tachycardia (MAT). In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

Idioventricular Rhythm
Gangwani MK, Nagalli S. Idioventricular Rhythm. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

March 24, 2020

Current Diagnosis and Management of Small-Cell Lung Cancer
Wang S, Zimmermann S, Parikh K, Mansfield AS, Adjei AA. Current Diagnosis and Management of Small-Cell Lung Cancer. Mayo Clin Proc. 2019;94(8):1599–1622. doi:10.1016/j.mayocp.2019.01.034

Hypertensive Emergencies: A Review of Common Presentations and Treatment Options
Brathwaite L, Reif M. Hypertensive Emergencies: A Review of Common Presentations and Treatment Options. Cardiol Clin. 2019;37(3):275–286. doi:10.1016/j.ccl.2019.04.003

Renin-Angiotensin-Aldosterone System
Lorenzo AJ. THE URINARY SYSTEM. In: Janson LW, Tischler ME. eds. The Big Picture: Medical Biochemistry New York, NY: McGraw-Hill; . http://accessmedicine.mhmedical.com.proxygw.wrlc.org/content.aspx?bookid=2355§ionid=185845372. Accessed March 24, 2020.
MLA Citation

Diagnosis and Differential Diagnosis of Cushing's Syndrome
Loriaux DL. Diagnosis and Differential Diagnosis of Cushing's Syndrome. N Engl J Med. 2017;376(15):1451–1459. doi:10.1056/NEJMra1505550

Cushing's disease: a multidisciplinary overview of the clinical features, diagnosis, and treatment
Buliman A, Tataranu LG, Paun DL, Mirica A, Dumitrache C. Cushing's disease: a multidisciplinary overview of the clinical features, diagnosis, and treatment. J Med Life. 2016;9(1):12–18.

March 18, 2020

Acute Pyelonephritis in Adults
Johnson JR, Russo TA. Acute Pyelonephritis in Adults [published correction appears in N Engl J Med. 2018 Mar 15;378(11):1069]. N Engl J Med. 2018;378(1):48–59. doi:10.1056/nejmcp1702758

Acute respiratory distress syndrome
Matthay MA, Zemans RL, Zimmerman GA, et al. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019;5(1):18. Published 2019 Mar 14. doi:10.1038/s41572-019-0069-0

Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment
Fan E, Brodie D, Slutsky AS. Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment. JAMA. 2018;319(7):698–710. doi:10.1001/jama.2017.21907

Acute Respiratory Distress Syndrome - NEJM review
Thompson BT, Chambers RC, Liu KD. Acute Respiratory Distress Syndrome. N Engl J Med. 2017;377(6):562–572. doi:10.1056/NEJMra1608077
Recommended by Dr. Ahari

Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review
Brodie D, Slutsky AS, Combes A. Extracorporeal Life Support for Adults With Respiratory Failure and Related Indications: A Review. JAMA. 2019;322(6):557–568. doi:10.1001/jama.2019.9302

March 13, 2020

Try-in-bud differential
Collins J. CT signs and patterns of lung disease. Radiol Clin North Am. 2001;39(6):1115–1135. doi:10.1016/s0033-8389(05)70334-1

Coccidioidomycosis (Valley Fever) in Primary Care
Herrick KR, Trondle ME, Febles TT. Coccidioidomycosis (Valley Fever) in Primary Care. Am Fam Physician. 2020;101(4):221–228.

Coccidioidomycosis
Parish JM, Blair JE. Coccidioidomycosis. Mayo Clin Proc. 2008;83(3):343–349. doi:10.4065/83.3.343

Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis
Thompson GR 3rd, Lewis JS 2nd, Nix DE, Patterson TF. Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis. Med Mycol. 2019;57(Supplement_1):S76–S84. doi:10.1093/mmy/myy029

March 11, 2020

Autoimmune hemolytic anemia
Hill A, Hill QA. Autoimmune hemolytic anemia. Hematology Am Soc Hematol Educ Program. 2018;2018(1):382–389. doi:10.1182/asheducation-2018.1.382

March 6, 2020

Post-traumatic headache
Ashina H, Porreca F, Anderson T, et al. Post-traumatic headache: epidemiology and pathophysiological insights. Nat Rev Neurol. 2019;15(10):607–617. doi:10.1038/s41582-019-0243-8

Diagnosis and Treatment of Pituitary Adenomas: A Review
Molitch ME. Diagnosis and Treatment of Pituitary Adenomas: A Review. JAMA. 2017;317(5):516–524. doi:10.1001/jama.2016.19699

Clinicopathology of pituitary adenomas
Lim CT, Korbonits M. UPDATE ON THE CLINICOPATHOLOGY OF PITUITARY ADENOMAS. Endocr Pract. 2018;24(5):473–488. doi:10.4158/EP-2018-0034

Pituitary apoplexy
Barkhoudarian G, Kelly DF. Pituitary Apoplexy. Neurosurg Clin N Am. 2019;30(4):457–463. doi:10.1016/j.nec.2019.06.001

March 2, 2020

Euglycemic diabetic ketoacidosis
Barski L, Eshkoli T, Brandstaetter E, Jotkowitz A. Euglycemic diabetic ketoacidosis. Eur J Intern Med. 2019;63:9–14. doi:10.1016/j.ejim.2019.03.014

Median arcuate ligament syndrome
Goodall R, Langridge B, Onida S, Ellis M, Lane T, Davies AH. Median arcuate ligament syndrome [published online ahead of print, 2019 Dec 24]. J Vasc Surg. 2019;S0741-5214(19)32642-4. doi:10.1016/j.jvs.2019.11.012

Nonthyroidal illness syndrome
Farwell AP. Nonthyroidal illness syndrome. Curr Opin Endocrinol Diabetes Obes. 2013;20(5):478–484. doi:10.1097/01.med.0000433069.09294.e8

Hypopituitarism
Alexandraki KI, Grossman A. Management of Hypopituitarism. J Clin Med. 2019;8(12):2153. Published 2019 Dec 5. doi:10.3390/jcm8122153

February 28, 2020

Muscle Weakness in Adults: Evaluation and Differential Diagnosis
Larson ST, Wilbur J. Muscle Weakness in Adults: Evaluation and Differential Diagnosis. Am Fam Physician. 2020;101(2):95–108.

Anion gap metabolic acidosis mnemonic: GOLD MARK

Review of the Diagnostic Evaluation of Renal Tubular Acidosis
Yaxley J, Pirrone C. Review of the Diagnostic Evaluation of Renal Tubular Acidosis. Ochsner J. 2016;16(4):525–530.

Acquired causes of Fanconi Syndrome
Fanconi Syndrome and Other Proximal Tubule Disorders in Comprehensive Clinical Nephropathy 6th ed.

Metabolic Acidosis
Metabolic Acidosis from in Comprehensive Clinical Nephropathy 6th ed.

February 27, 2020

Cerebral Venous Thrombosis
Ferro JM, Aguiar de Sousa D. Cerebral Venous Thrombosis: an Update. Curr Neurol Neurosci Rep. 2019;19(10):74. Published 2019 Aug 23. doi:10.1007/s11910-019-0988-x

FLAT PIG mnemonic
Six hormones of the anterior pituitary.

Primary empty sella
Chiloiro S, Giampietro A, Bianchi A, et al. DIAGNOSIS OF ENDOCRINE DISEASE: Primary empty sella: a comprehensive review. Eur J Endocrinol. 2017;177(6):R275–R285. doi:10.1530/EJE-17-0505

Orbital cellulitis
Tsirouki T, Dastiridou AI, Ibánez Flores N, et al. Orbital cellulitis. Surv Ophthalmol. 2018;63(4):534–553. doi:10.1016/j.survophthal.2017.12.001

Hypersensitivity pneumonitis
Sahin H, Kaproth-Joslin K, Hobbs SK. Hypersensitivity Pneumonitis. Semin Roentgenol. 2019;54(1):37–43. doi:10.1053/j.ro.2018.12.004

February 21, 2020

Extracorporeal membrane oxygenation in adults: A practical guide for internists
Kulkarni T, Sharma NS, Diaz-Guzman E. Extracorporeal membrane oxygenation in adults: A practical guide for internists. Cleve Clin J Med. 2016;83(5):373–384. doi:10.3949/ccjm.83a.15021

Venoarterial ECMO for Adults (CME/MOC/ECME Activity)
Guglin M, Zucker MJ, Bazan VM, et al. Venoarterial ECMO for Adults: JACC Scientific Expert Panel. J Am Coll Cardiol. 2019;73(6):698–716. doi:10.1016/j.jacc.2018.11.038

Contemporary Comprehensive Monitoring of Veno-arterial Extracorporeal Membrane Oxygenation Patients
Bhatia M, Katz JN. Contemporary Comprehensive Monitoring of Veno-arterial Extracorporeal Membrane Oxygenation Patients. Can J Cardiol. 2020;36(2):291–299. doi:10.1016/j.cjca.2019.10.031

ESCAPE trial
Binanay C, Califf RM, Hasselblad V, et al. Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA. 2005;294(13):1625–1633. doi:10.1001/jama.294.13.1625

February 20, 2020

Hypersensitivity pneumonitis
Sahin H, Kaproth-Joslin K, Hobbs SK. Hypersensitivity Pneumonitis. Semin Roentgenol. 2019;54(1):37–43. doi:10.1053/j.ro.2018.12.004

Peripartum cardiomyopathy
Garg J, Palaniswamy C, Lanier GM. Peripartum cardiomyopathy: definition, incidence, etiopathogenesis, diagnosis, and management. Cardiol Rev. 2015;23(2):69–78. doi:10.1097/CRD.0000000000000038

Rhabdomyolysis
Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury [published correction appears in N Engl J Med. 2011 May 19;364(20):1982]. N Engl J Med. 2009;361(1):62–72. doi:10.1056/NEJMra0801327

Rhabdomyolysis and aldolase deficiency
Mamoune A, Bahuau M, Hamel Y, et al. A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia. PLoS Genet. 2014;10(11):e1004711. Published 2014 Nov 13. doi:10.1371/journal.pgen.1004711

February 14, 2020

Tuberculous meningitis review
Wilkinson RJ, Rohlwink U, Misra UK, et al. Tuberculous meningitis. Nat Rev Neurol. 2017;13(10):581–598. doi:10.1038/nrneurol.2017.120

Tuberculous meningitis
Slane VH, Unakal CG. Tuberculous Meningitis. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2020.

The neurocritical care of tuberculous meningitis
Donovan J, Figaji A, Imran D, Phu NH, Rohlwink U, Thwaites GE. The neurocritical care of tuberculous meningitis. Lancet Neurol. 2019;18(8):771–783. doi:10.1016/S1474-4422(19)30154-1

Brucellosis in Humans--Etiology, Diagnostics, Clinical Forms
Galińska EM, Zagórski J. Brucellosis in humans--etiology, diagnostics, clinical forms. Ann Agric Environ Med. 2013;20(2):233–238.

Leptospirosis
Karpagam KB, Ganesh B. Leptospirosis: a neglected tropical zoonotic infection of public health importance-an updated review [published online ahead of print, 2020 Jan 2]. Eur J Clin Microbiol Infect Dis. 2020;10.1007/s10096-019-03797-4. doi:10.1007/s10096-019-03797-4

Hepatic Echinococcal Cysts: A Review
Pakala T, Molina M, Wu GY. Hepatic Echinococcal Cysts: A Review. J Clin Transl Hepatol. 2016;4(1):39–46. doi:10.14218/JCTH.2015.00036

February 10, 2020

Colorectal Cancer Screening and Prevention
Wilkins T, McMechan D, Talukder A. Colorectal Cancer Screening and Prevention. Am Fam Physician. 2018;97(10):658–665.

Colorectal adenomas
Strum WB. Colorectal Adenomas. N Engl J Med. 2016;374(11):1065–1075. doi:10.1056/NEJMra1513581

Colorectal cancer
Dekker E, Tanis PJ, Vleugels JLA, Kasi PM, Wallace MB. Colorectal cancer. Lancet. 2019;394(10207):1467–1480. doi:10.1016/S0140-6736(19)32319-0

February 5, 2020

Serotonin syndrome
Wang RZ, Vashistha V, Kaur S, Houchens NW. Serotonin syndrome: Preventing, recognizing, and treating it. Cleve Clin J Med. 2016;83(11):810–817. doi:10.3949/ccjm.83a.15129

Identifying and treating patients with synthetic psychoactive drug intoxication
Brown GR, McLaughlin K, Vaughn K. Identifying and treating patients with synthetic psychoactive drug intoxication. JAAPA. 2018;31(8):1–5. doi:10.1097/01.JAA.0000541487.41149.71

Neuroleptic Malignant Syndrome
Pileggi DJ, Cook AM. Neuroleptic Malignant Syndrome. Ann Pharmacother. 2016;50(11):973–981. doi:10.1177/1060028016657553

Serotonin syndrome
Dr. Ahari recommends flow chart
Boyer EW, Shannon M. The serotonin syndrome [published correction appears in N Engl J Med. 2007 Jun 7;356(23):2437] [published correction appears in N Engl J Med. 2009 Oct 22;361(17):1714]. N Engl J Med. 2005;352(11):1112–1120. doi:10.1056/NEJMra041867

February 3, 2020

Renal infarction
From Comprehensive Clinical Nephrology 6th ed.)

Thrombophilia workup
Connors JM. Thrombophilia Testing and Venous Thrombosis. N Engl J Med. 2017;377(12):1177–1187. doi:10.1056/NEJMra1700365

Hypercoagulable states in arterial and venous thrombosis: When, how, and who to test?
Carroll BJ, Piazza G. Hypercoagulable states in arterial and venous thrombosis: When, how, and who to test?. Vasc Med. 2018;23(4):388–399. doi:10.1177/1358863X18755927

Screening for Occult Cancer in Unprovoked Venous Thromboembolism
Carrier M, Lazo-Langner A, Shivakumar S, et al. Screening for Occult Cancer in Unprovoked Venous Thromboembolism. N Engl J Med. 2015;373(8):697–704. doi:10.1056/NEJMoa1506623

January 29, 2020

Clostridioides difficile Infection
Guh AY, Kutty PK. Clostridioides difficile Infection. Ann Intern Med. 2018;169(7):ITC49–ITC64. doi:10.7326/AITC201810020

How long does toxin test remain positive?
"...toxins remain detectable in 7% (2/28) of patients at the end of treatment for C difficile infection and as many as 56% (15/27) of patients with C difficile infection have positive stool cultures 1-4 weeks after therapy, despite resolution of diarrhea."
Guery B, Galperine T, Barbut F. Clostridioides difficile: diagnosis and treatments. BMJ. 2019;366:l4609. Published 2019 Aug 20. doi:10.1136/bmj.l4609

January 27, 2020

Methotrexate toxicity and adverse reactions
From Meyler’s Side Effects of Drugs

Methotrexate
From Rheumatology (7th Ed.)

January 17, 2020

Epilepsy
Devinsky O, Vezzani A, O'Brien TJ, et al. Epilepsy. Nat Rev Dis Primers. 2018;4:18024. Published 2018 May 3. doi:10.1038/nrdp.2018.24

Epilepsy
Thijs RD, Surges R, O'Brien TJ, Sander JW. Epilepsy in adults. Lancet. 2019;393(10172):689–701. doi:10.1016/S0140-6736(18)32596-0

Auras
Fried I. Auras and experiential responses arising in the temporal lobe. J Neuropsychiatry Clin Neurosci. 1997;9(3):420–428. doi:10.1176/jnp.9.3.420

Therapeutic Hypothermia for Refractory Status Epilepticus
Zeiler FA, Zeiler KJ, Teitelbaum J, Gillman LM, West M. Therapeutic Hypothermia for Refractory Status Epilepticus. Can J Neurol Sci. 2015;42(4):221–229. doi:10.1017/cjn.2015.31

Update on Antiepileptic Drugs 2019
Abou-Khalil BW. Update on Antiepileptic Drugs 2019. Continuum (Minneap Minn). 2019;25(2):508–536. doi:10.1212/CON.0000000000000715

Increased seizures during pregnancy?
Tomson T, Hiilesmaa V. Epilepsy in pregnancy. BMJ. 2007;335(7623):769–773. doi:10.1136/bmj.39266.473113.BE

January 13, 2020

Pheochromocyroma
Sbardella E, Grossman AB. Pheochromocytoma: An approach to diagnosis [published online ahead of print, 2019 Oct 22]. Best Pract Res Clin Endocrinol Metab. 2019;101346. doi:10.1016/j.beem.2019.101346

Secondary hypertension
Charles L, Triscott J, Dobbs B. Secondary Hypertension: Discovering the Underlying Cause. Am Fam Physician. 2017;96(7):453–461.

January 10, 2020

Neonatal lupus
Vanoni F, Lava SAG, Fossali EF, et al. Neonatal Systemic Lupus Erythematosus Syndrome: a Comprehensive Review. Clin Rev Allergy Immunol. 2017;53(3):469–476. doi:10.1007/s12016-017-8653-0

Clinical Evaluation of Bleeding and Bruising in Primary Care
Neutze D, Roque J. Clinical Evaluation of Bleeding and Bruising in Primary Care. Am Fam Physician. 2016;93(4):279–286.

How I investigate for bleeding disorders
Hayward CPM. How I investigate for bleeding disorders. Int J Lab Hematol. 2018;40 Suppl 1:6–14. doi:10.1111/ijlh.12822

Bleeding Diatheses: Approach to the Patient Who Bleeds or Has Abnormal Coagulation
Paddock M, Chapin J. Bleeding Diatheses: Approach to the Patient Who Bleeds or Has Abnormal Coagulation. Prim Care. 2016;43(4):637–650. doi:10.1016/j.pop.2016.07.009

Acquired hemophilia
Kruse-Jarres R, Kempton CL, Baudo F, et al. Acquired hemophilia A: Updated review of evidence and treatment guidance. Am J Hematol. 2017;92(7):695–705. doi:10.1002/ajh.24777

January 9, 2020

Lipoid pneumonia

Diagnosis and management of interstitial lung diseases
Wallis A, Spinks K. The diagnosis and management of interstitial lung diseases. BMJ. 2015;350:h2072. Published 2015 May 7. doi:10.1136/bmj.h2072

Acute liver failure
Stravitz RT, Lee WM. Acute liver failure. Lancet. 2019;394(10201):869–881. doi:10.1016/S0140-6736(19)31894-X

Internal Medicine Residency Readings: Jan - June 2020

Critical Care Primer

Education

June 2, 2020

May 28, 2020

May 21, 2020

May 19, 2020

May 14, 2020

May 12, 2020

May 7, 2020

May 5, 2020

April 30, 2020

April 28, 2020

April 23, 2020

April 22, 2020

April 16, 2020

April 14, 2020

April 9, 2020

April 7, 2020

April 2, 2020

March 31, 2020

March 26, 2020

March 24, 2020

March 18, 2020

March 13, 2020

March 11, 2020

March 6, 2020

March 2, 2020

February 28, 2020

February 27, 2020

February 21, 2020

February 20, 2020

February 14, 2020

February 10, 2020

February 5, 2020

February 3, 2020

January 29, 2020

January 27, 2020

January 17, 2020

January 13, 2020

January 10, 2020

January 9, 2020