Internal Medicine Residency Readings: Critical Care

PRISM Investigators, Rowan KM, Angus DC, et al. Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis. N Engl J Med. 2017;376(23):2223-2234. doi:10.1056/NEJMoa1701380

ProCESS Investigators. (2014). A randomized trial of protocol-based care for early septic shock. N Engl J Med, 2014(370), 1683-1693.

Dugar S, Choudhary C, Duggal A. Sepsis and septic shock: Guideline-based management. Cleve Clin J Med. 2020;87(1):53–64. doi:10.3949/ccjm.87a.18143

Ramanan, M., Cohen, J., & Venkatesh, B. (2019). Steroids and Sepsis: the Debate Continues. International anesthesiology clinics, 57(2), 17–30. https://doi.org/10.1097/AIA.0000000000000220

Modi AR, Kovacs CS. Hospital-acquired and ventilator-associated pneumonia: Diagnosis, management, and prevention. Cleve Clin J Med. 2020;87(10):633-639. Published 2020 Oct 1. doi:10.3949/ccjm.87a.19117

Wick KD, Ware LB, Matthay MA. Acute respiratory distress syndrome. BMJ. 2024 Oct 28;387:e076612. doi: 10.1136/bmj-2023-076612. PMID: 39467606.

El Farissi M, Keulards DCJ, Zelis JM, et al. Hypothermia for Reduction of Myocardial Reperfusion Injury in Acute Myocardial Infarction: Closing the Translational Gap. Circ Cardiovasc Interv. 2021;14(8):e010326. doi:10.1161/CIRCINTERVENTIONS.120.010326

Page V, McKenzie C. Sedation in the Intensive Care Unit. Curr Anesthesiol Rep. 2021;11(2):92-100. doi:10.1007/s40140-021-00446-5

Sharma, S., Hashmi, M. F., & Valentino III, D. J. (2020). Sedation Vacation in the ICU. In StatPearls. StatPearls Publishing.

Gunst, J., De Bruyn, A., & Van den Berghe, G. (2019). Glucose control in the ICU. Current opinion in anaesthesiology, 32(2), 156–162. https://doi.org/10.1097/ACO.0000000000000706

Hébert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., ... & Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group. (1999). A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. New England Journal of Medicine, 340(6), 409-417.

Carson JL, Stanworth SJ, Guyatt G, et al. Red Blood Cell Transfusion: 2023 AABB International Guidelines. JAMA. 2023;330(19):1892-1902. doi:10.1001/jama.2023.12914

Kupfer Y, Cappell MS, Tessler S. Acute gastrointestinal bleeding in the intensive care unit. The intensivist's perspective. Gastroenterol Clin North Am. 2000 Jun;29(2):275-307, v. Review. PubMed PMID: 10836184.

Shingina A, Mukhtar N, Wakim-Fleming J, et al. Acute Liver Failure Guidelines. Am J Gastroenterol. 2023;118(7):1128-1153. doi:10.14309/ajg.0000000000002340

Thachil J, Warkentin TE. How do we approach thrombocytopenia in critically ill patients? Br J Haematol. 2017 Apr;177(1):27-38. doi: 10.1111/bjh.14482. Epub 2016 Dec 16. Review. PubMed PMID: 27982413.

Gould Rothberg BE, Quest TE, Yeung SJ, et al. Oncologic emergencies and urgencies: A comprehensive review. CA Cancer J Clin. 2022;72(6):570-593. doi:10.3322/caac.21727

Husebye ES, Pearce SH, Krone NP, Kämpe O. Adrenal insufficiency. Lancet. 2021 Jan 20:S0140-6736(21)00136-7. doi: 10.1016/S0140-6736(21)00136-7. Epub ahead of print. PMID: 33484633.

Ylli, D., Klubo-Gwiezdzinska, J., & Wartofsky, L. (2019). Thyroid emergencies. Polish archives of internal medicine, 129(7-8), 526–534. https://doi.org/10.20452/pamw.14876

Torres, C. & Haut, E. R. (2020). Prevention, diagnosis, and management of venous thromboembolism in the critically ill surgical and trauma patient. Current Opinion in Critical Care, 26 (6), 640-647. doi: 10.1097/MCC.0000000000000771.

Szymanski, K., Weber, C., Daugherty, K., & Cohen, D. A. (2025). A review of venous thromboembolism for the hospitalist. Postgraduate medicine, 137(2), 131–138. https://doi.org/10.1080/00325481.2025.2452155

Pflipsen, M. C., & Vega Colon, K. M. (2020). Anaphylaxis: Recognition and Management. American family physician, 102(6), 355–362.

Kopp Lugli, A., de Watteville, A., Hollinger, A., Goetz, N., & Heidegger, C. (2019). Medical Nutrition Therapy in Critically Ill Patients Treated on Intensive and Intermediate Care Units: A Literature Review. Journal of clinical medicine, 8(9), 1395. https://doi.org/10.3390/jcm8091395

Finfer, S., Myburgh, J., & Bellomo, R. (2018). Intravenous fluid therapy in critically ill adults. Nature reviews. Nephrology, 14(9), 541–557. https://doi.org/10.1038/s41581-018-0044-0

Mederos, M. A., Reber, H. A., & Girgis, M. D. (2021). Acute Pancreatitis: A Review. JAMA, 325(4), 382–390. https://doi.org/10.1001/jama.2020.20317