Research Guides: Internal Medicine Residency Readings: Critical Care

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Critical Care

Goal-Directed Resuscitation for Patients with Early Septic Shock (ARISE trial)
Arise Investigators, and ANZICS Clinical Trials Group. "Goal-directed resuscitation for patients with early septic shock." N Engl J Med 2014.371 (2014): 1496-1506.
A Randomized Trial of Protocol-Based Care for Early Septic Shock (ProCESS trial)
ProCESS Investigators. (2014). A randomized trial of protocol-based care for early septic shock. N Engl J Med, 2014(370), 1683-1693.
Sepsis and septic shock management
Dugar S, Choudhary C, Duggal A. Sepsis and septic shock: Guideline-based management. Cleve Clin J Med. 2020;87(1):53–64. doi:10.3949/ccjm.87a.18143
Sepsis and steroids
Annane D. The Role of ACTH and Corticosteroids for Sepsis and Septic Shock: An Update. Front Endocrinol (Lausanne). 2016 Jun 20;7:70. doi: 10.3389/fendo.2016.00070. eCollection 2016. Review. PubMed PMID: 27379022; PubMed Central PMCID: PMC4913096.
Ventilator-associated pneumonia
Nair GB, Niederman MS. Ventilator-associated pneumonia: present understanding and ongoing debates. Intensive Care Med. 2015 Jan;41(1):34-48. doi: 10.1007/s00134-014-3564-5. Epub 2014 Nov 27. Review. PubMed PMID: 25427866.
Acute Respiratory Distress Syndrome
Thompson BT, Chambers RC, Liu KD. Acute Respiratory Distress Syndrome. N Engl J Med. 2017 Aug 10;377(6):562-572. doi: 10.1056/NEJMra1608077. Review. PubMed PMID: 28792873.
Therapeutic hypothermia post MI
Kang IS, Fumiaki I, Pyun WB. Therapeutic Hypothermia for Cardioprotection in Acute Myocardial Infarction. Yonsei Med J. 2016 Mar;57(2):291-7. doi: 10.3349/ymj.2016.57.2.291. Review. PubMed PMID: 26847278; PubMed Central PMCID: PMC4740518.
Sedation options
Reade MC, Finfer S. Sedation and delirium in the intensive care unit. N Engl J Med. 2014 Jan 30;370(5):444-54. doi: 10.1056/NEJMra1208705. Review. PubMed PMID: 24476433.
Sedation holiday/sedation interruptions
Roberts DJ, Haroon B, Hall RI. Sedation for critically ill or injured adults in the intensive care unit: a shifting paradigm. Drugs. 2012 Oct 1;72(14):1881-916. doi: 10.2165/11636220-000000000-00000. Review. PubMed PMID: 22950534.
Glycemic control in the intensive care unit
Samokhvalov A, Farah R, Makhoul N. lycemic control in the intensive care unit: between safety and benefit. Isr Med Assoc J. 2012 Apr;14(4):260-6. Review. PubMed PMID: 22675848.
Transfusion requirements in critical care (TRICC Trial)
Hébert, P. C., Wells, G., Blajchman, M. A., Marshall, J., Martin, C., Pagliarello, G., ... & Transfusion Requirements in Critical Care Investigators for the Canadian Critical Care Trials Group. (1999). A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. New England Journal of Medicine, 340(6), 409-417.
I bleeding in ICU patients
Kupfer Y, Cappell MS, Tessler S. Acute gastrointestinal bleeding in the intensive care unit. The intensivist's perspective. Gastroenterol Clin North Am. 2000 Jun;29(2):275-307, v. Review. PubMed PMID: 10836184.
Acute liver failure
Rajaram P, Subramanian R. Acute Liver Failure. Semin Respir Crit Care Med. 2018;39(5):513–522. doi:10.1055/s-0038-1673372
Thrombocytopenia in critically ill patients
Thachil J, Warkentin TE. How do we approach thrombocytopenia in critically ill patients? Br J Haematol. 2017 Apr;177(1):27-38. doi: 10.1111/bjh.14482. Epub 2016 Dec 16. Review. PubMed PMID: 27982413.
Oncologic emergencies
Pi J, Kang Y, Smith M, Earl M, Norigian Z, McBride A. A review in the treatment of oncologic emergencies. J Oncol Pharm Pract. 2016 Aug;22(4):625-38. doi: 10.1177/1078155215605661. Epub 2015 Oct 6. Review. PubMed PMID: 26447101
Adrenal insufficiency
Husebye ES, Pearce SH, Krone NP, Kämpe O. Adrenal insufficiency. Lancet. 2021 Jan 20:S0140-6736(21)00136-7. doi: 10.1016/S0140-6736(21)00136-7. Epub ahead of print. PMID: 33484633.
Myxedema coma
Wiersinga WM. Myxedema and Coma (Severe Hypothyroidism). 2015 Apr 12. In: De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from http://www.ncbi.nlm.nih.gov/books/NBK279007/ PubMed PMID: 25905238.
Venous thromboembolism in the ICU
Minet C, Potton L, Bonadona A, Hamidfar-Roy R, Somohano CA, Lugosi M, Cartier JC, Ferretti G, Schwebel C, Timsit JF. Venous thromboembolism in the ICU: main characteristics, diagnosis and thromboprophylaxis. Crit Care. 2015 Aug 18;19:287. doi: 10.1186/s13054-015-1003-9. Review. PubMed PMID: 26283414; PubMed Central PMCID: PMC4539929.
Anaphylaxis
Hernandez L, Papalia S, Pujalte GG. Anaphylaxis. Prim Care. 2016 Sep;43(3):477-85. doi: 10.1016/j.pop.2016.04.002. Review. PubMed PMID: 27545736.
Nutrition in critically ill patients
Casaer MP, Van den Berghe G. Nutrition in the acute phase of critical illness. N Engl J Med. 2014 Mar 27;370(13):1227-36. doi: 10.1056/NEJMra1304623. Review. PubMed PMID: 24670169.
Intravenous fluid therapy in adult inpatients
Frost P. Intravenous fluid therapy in adult inpatients. BMJ. 2015 Jan 6;350:g7620. doi: 10.1136/bmj.g7620. PubMed PMID: 25569336.